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Meng-Jer Hsieh, M.D.


Meng-Jer Hsieh, M.D.
Assistant Professor, Department of Respiratory Therapy

Tel: +886- 5-3621000#2762
E-mail: mengjer@adm.cgmh.org.tw


School of Medicine, Kaohsiung Medical University


Pulmonary and Critical Medicine

Academic Appointment

  • 2011 – Today  Assistant Professor Chang Gung university
  • 2014 – Today  Chief Division of Chest Medicine (CGMH in Chiayi)


  1. Ming-Lung Chuang, Meng-Jer Hsieh, Tzu-ChinWu & I-Feng Lin. Developing a New Marker of Dynamic Hyperinflation in Patients with Obstructive Airway Disease - an observational study. Scientific Report 2019.
  2. Li SH, Hsieh MJ, Lin SW, Chuang LP, Lee CS, Chiu LC, et al. Outcomes of severe H1N1 pneumoniae: A retrospective study at intensive care units. J Formos Med Assoc. 2019.
  3. Chuang LP, Lin SW, Lee LA, Chang CH, Huang HY, Hu HC, et al. Elevated Serum Markers of Acute Kidney Injury in Patients With Obstructive Sleep Apnea. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 2019;15(2):207-13.
  4. Chen NH, Lin SW, Chuang LP, Cistulli PA, Hsieh MJ, Kao KC, et al. Pharyngeal distensibility during expiration is an independent predictor of the severity of obstructive sleep apnoea. Respirology. 2019.
  5. Hsieh, M. J., H. C. Hu, K. C. Kao, H. Y. Cho, C. C. Huang, N. H. Chen, Y. L. Chou, C. H. Chang and Y. H. Tsai. "The Risk of Latent Tuberculosis Infection in Respiratory Therapists in a Country with Intermediate Incidence." Respir Care, Nov 13, 2018. DOI: 10.4187/respcare.06316
  6. Chuang, M. C., C. H. Chang, C. S. Lee, S. H. Li, C. C. Hsiao, Y. F. Fang and M. J. Hsieh. One-year mortality among hospital survivors of cholinesterase inhibitor poisoning based on Taiwan National Health Insurance Research Database from 2003 to 2012. BMC Pharmacol Toxicol 19(1): 72. (Corresponding author)
  7. Meng-Jer Hsieh, Shu-Yi Huang, Tsung-Ming Yang, et, al. The impact of 2011 and 2017 Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) guidelines on allocation and pharmacological management of patients with COPD in Taiwan: Taiwan Obstructive Lung Disease (TOLD) study. International Journal of COPD 2018:13 2949–2959
  8. Hsieh MJ, Lin YC, Lai RS, Wu CL, Lai CL, Wang CC, et al. Comparative efficacy and tolerability of beclomethasone/formoterol and fluticasone/salmeterol fixed combination in Taiwanese asthmatic patients. J Formos Med Assoc. 2018;117(12):1078-85.
  9. Kao KC, Hsieh MJ, Lin SW, Chuang LP, Chang CH, Hu HC, Wang CH, Li LF, Huang CC, Wu HP. Survival predictors in elderly patients with acute respiratory distress syndrome: a prospective observational cohort study. Sci Rep. 2018 Sep 7;8(1):13459. doi: 10.1038/s41598-018-31811-w
  10. Meng-Jer Hsieh, Wei-Chun Lee, Hsiu-Ying Cho, Meng-Fang Wu, Han-Chung Hu, Kuo-Chin Kao, Ning-Hung Chen, Ying-Huang Tsai and Chung-Chi-Huang. Recovery of Pulmonary functions, Exercise Capacity and Quality of Life after Pulmonary Rehabilitation in Survivors of ARDS due to Severe Influenza A (H1N1) Pneumonitis. Influenza Other Respir Viruses. 2018 Sep; 12(5): 643–648. Published online 2018 Jun 12. doi: 10.1111/irv.12566
  11. Chuang MC, Yang YH, Tsai YH, et al. Survival benefit associated with metformin use in inoperable non-small cell lung cancer patients with diabetes: A population-based retrospective cohort study. PLoS One. 2018;13(1):e0191129.
  12. Lin HL, Fang TP, Cho HS, et al. Aerosol delivery during spontaneous breathing with different types of nebulizers-in vitro/ex vivo models evaluation. Pulmonary pharmacology & therapeutics 2017 doi: 10.1016/j.pupt.2017.12.006 [published Online First: 2017/12/27]
  13. Chuang ML, Lin IF, Huang SF, Hsieh MJ. Patterns of Oxygen Pulse Curve in Response to Incremental Exercise in Patients with Chronic Obstructive Pulmonary Disease - An Observational Study. Scientific reports 2017;7(1):10929.
  14. Fang YH, Hsu CC, Hsieh MJ, et al. Impact of hypertrophic pulmonary osteoarthropathy on patients with lung cancer. Onco Targets Ther 2017;10:5173-77. doi: 10.2147/ott.s139558 [published Online First: 2017/11/11]
  15. Wang WC, Lu ML, Chen VC, et al. Asthma, corticosteroid use and schizophrenia: A nationwide population-based study in Taiwan. PLoS One. 2017;12(3):e0173063.
  16. Chang GC, Tseng CH, Hsu KH, et al. Predictive factors for EGFR-tyrosine kinase inhibitor retreatment in patients with EGFR-mutated non-small-cell lung cancer - A multicenter retrospective SEQUENCE study. Lung Cancer 2017;104:58-64. doi: 10.1016/j.lungcan.2016.12.002
  17. Hsieh MJ, Yang TM, Tsai YH. Nutritional supplementation in patients with chronic obstructive pulmonary disease. J Formos Med Assoc. 2016;115(8):595-601.
  18. Hung MS, Lung JH, Lin YC, Fang YH, Hsieh MJ, Tsai YH. The content of mutant EGFR DNA correlates with response to EGFR-TKIs in lung adenocarcinoma patients with common EGFR mutations. Medicine (Baltimore). 2016;95(26):e3991.
  19. Chuang MC, Chou YT, Lin YC, Hsieh MJ, Tsai YH. Diffuse panbronchiolitis-The response and recurrence after erythromycin therapy. J Formos Med Assoc. 2016;115(10):876-882.
  20. Ying-Huang Tsai; Meng-Jer Hsieh; Chee-Jen Chang; Yu-Wen Wen; Han-Chung Hu; Yen-Nan Chao; Yhu-Chering Huang; Cheng-Ta Yang; Chung-Chi Huang. The 23-valent pneumococcal polysaccharide vaccine is effective in elderly adults over 75 years old - Taiwan's PPV vaccination program. Vaccine 2015: 33(25), 2897-2902 (Co-first Author)
  21. Chang CH, Tsao KC, Hu HC, Huang CC, Kao KC, Chen NH, Yang CT, Tsai YH, Hsieh MJ. Procalcitonin and C-reactive protein cannot differentiate bacterial or viral infection in COPD exacerbation requiring emergency department visits. International Journal of COPD 2015:10(1), 767-774. DOI http://dx.doi.org/10.2147/COPD.S76740 (Corresponding author)
  22. Wu MF, Li YS, Hung CY, Chao WC, Fu ZY, Kao KC, Huang CC, Tsai YH, Hsieh MJ. Relapsing Polychondritis With Initial Presentations of Recurrent Negative-Pressure Pulmonary Edema and Acute Respiratory Failure. Respir Care. 2015 May;60(5):e101-4. doi: 10.4187/respcare.03274. Epub 2014 Dec 30. (corresponding author)
  23. Hu HC, Liu HC, Chen YH, et al. The impact of aerosolized mucolytic agents on the airflow resistance of bacterial filters used in mechanical ventilation. J Formos Med Assoc 2015;114(8):717-21. doi: 10.1016/j.jfma.2013.06.010 [published Online First: 2013/07/23]
  24. Kao KC, Hu HC, Hsieh MJ, et al. Comparison of community-acquired, hospital-acquired, and intensive care unit-acquired acute respiratory distress syndrome: a prospective observational cohort study. Crit Care 2015;19:384. doi: 10.1186/s13054-015-1096-1
  25. Hung MS, Chen IC, You L, et al. Knockdown of Cul4A increases chemosensitivity to gemcitabine through upregulation of TGFBI in lung cancer cells. Oncol Rep 2015;34(6):3187-95. doi: 10.3892/or.2015.4324
  26. Hung CY, Kao KC, Wang PN, Hu HC, Hsieh MJ, Fu JY, Chang CH, Li LF, Huang CC, Tsai YH, Yang CT. Invasive fungal infection among hematopoietic stem cell transplantation patients with mechanical ventilation in the intensive care unit. BMC Infect Dis. 2012 Feb 18;12:44. doi: 10.1186/1471-2334-12-44. PubMed PMID:22339791; PubMed Central PMCID: PMC3298694.
  27. Lin C-M, Shieh W-B, Chiang P-C, Hsieh M-J, Liu Y-C, Chiou C-C, et al. An unusual cause of dyspnea in a patient with cervical herpes zoster. Journal of Clinical Neuroscience 2012;19(4):608-09. doi: http://dx.doi.org/10.1016/j.jocn.2011.06.023
  28. Huang CH, Hu HC, Hsieh MJ, et al. High-frequency oscillatory ventilation for rescue from refractory hypoxemia in a patient with transfusion-related acute lung injury. Respir Care. United States 2012:798-801.
  29. Kao KC, Hu HC, Fu JY, Hsieh MJ, Wu YK, Chen YC, Chen YH, Huang CC, Yang CT, Tsai YH. Renal replacement therapy in prolonged mechanical ventilation patients with renal failure in Taiwan. J Crit Care. 2011 Dec;26(6):600-7. doi: 10.1016/j.jcrc.2011.03.005. Epub 2011 Jun 12. PubMed PMID: 21664102.
  30. Huang CC, Kao KC, Fu JY, Hsieh MJ. Effects of extravascular lung water on the measurement of transpulmonary thermodilution cardiac output in acute respiratory distress syndrome patients. J Cardiothorac Vasc Anesth. 2011 Jun;25(3):481-5. doi: 10.1053/j.jvca.2010.07.005. Epub 2010 Sep 9. PubMed PMID: 20829067.
  31. Kuo YB, Chang CA, Wu YK, Hsieh MJ, Tsai CH, Chen KT, Chen CY, Chan EC. Identification and clinical association of anti-cytokeratin 18 autoantibody in COPD. Immunol Lett. 2010 Feb 16;128(2):131-6. doi: 10.1016/j.imlet.2009.12.017. Epub 2009 Dec 28. PubMed PMID: 20038439.
  32. Huang CC, Kao KC, Hsu KH, Ko HW, Li LF, Hsieh MJ, et al. Effects of hydroxyethyl starch resuscitation on extravascular lung water and pulmonary permeability in sepsis-related acute respiratory distress syndrome. Crit Care Med 2009;37(6):1948-55.
  33. Hsieh MJ, Liang HW, Chiang PC, et al. Delayed Suspicion, Treatment and Isolation of Tuberculosis Patients in Pulmonology/Infectious Diseases and Non-Pulmonology/Infectious Diseases Wards. J Formos Med Assoc. 2009;108(3):202-209.
  34. Wu YK, Kao KC, Hsu KH, Hsieh MJ, Tsai YH. Predictors of successful weaning from prolonged mechanical ventilation in Taiwan. Respir Med. Aug 2009;103(8):1189-1195.
  35. Huang CC, Kao KC, Hsu KH, et al. Effects of hydroxyethyl starch resuscitation on extravascular lung water and pulmonary permeability in sepsis-related acute respiratory distress syndrome. Crit Care Med. Jun 2009;37(6):1948-1955.
  36. Lin CS, Hsieh MJ, Y.H. T. Non-invasive Management of Chylothorax Secondary to Liver Cirrhosis -- Report of a Case Thoracic Medicine. 2008;23(2).
  37. Huang CC, Fu JY, Hu HC, et al. Prediction of fluid responsiveness in acute respiratory distress syndrome patients ventilated with low tidal volume and high positive end-expiratory pressure. Crit Care Med. Oct 2008;36(10):2810-2816.
  38. Hsieh MJ, Lan CC, Chen NH, et al. Effects of high-intensity exercise training in a pulmonary rehabilitation programme for patients with chronic obstructive pulmonary disease. Respirology. May 2007;12(3):381-388.
  39. Yang TM, Wang PN, Kao KC, Huang CC, Tsai YH, Hsieh MJ. Outcome of hematopoietic stem cell recipients who were mechanically ventilated and admitted to intensive care units. J Formos Med Assoc. Apr 2007;106(4):295-301.
  40. Lin CH, Hsieh MJ, Lin CK, Hung MS, Leu SW. Pulmonary Infection due to Mycobacterium Lentiflavum — A Case Report. Thracic Medicine. 2007;22(5):355-360.
  41. Chou YT, Wu YK, Hu HC, Hsieh MJ. Pulmonary Infection with Mycobacterium simiae – A Case Report. Thoracic Medicine. 2007;22:27-32.
  42. Chen NH, Wang PC, Hsieh MJ, et al. Impact of severe acute respiratory syndrome care on the general health status of healthcare workers in taiwan. Infection Control & Hospital Epidemiology. Jan 2007;28(1):75-79.
  43. Kao KC, Wu YK, Huang CC, Hsieh MJ, Tsai YH. Recurrent life threatening massive hemoptysis as a presentation of pulmonary actinomycosis. Chang Gung Med J. 2006;29(4 Suppl):66-70.
  44. Kao KC, Tsai YH, Wu YK, et al. Open lung biopsy in early-stage acute respiratory distress syndrome. Critical Care (London, England). 2006;10(4):R106.
  45. Chuang LP, Wang CL, Chen CH, Hsieh MJ. Delayed Diagnosis of an Endobronchial Foreign Body - the Indication of Bronchoscopy in Pregnant Women : A Case Report. Thoracic Medicine. 2006;21:452-456.
  46. Hu HC, Huang CC, Tsai YH, Lee CH,. Outcome Analysis of Patients Requiring Mechanical Ventilation with Severe Community-Acquired Pneumonia and Identified Bacterial Pathogens. Chang Hsieh MJ Gung Med J. 2005;28(4):229-236.
  47. Hsiung TC, Hsieh MJ, Chuang ML, Lim KE, Tsai YH. Cardiopulmonary Exercise Test in a Patient with Pulmonary Arteriovenous Malformation: A Case Report. Thoracic Medicine. 2005;20(6):697-702.
  48. Hsieh MJ, Junquiera-Kipnis A, Hoeffer A, Turner OC, Orme IM. Incorporation of CpG Oligodeoxynucleotide fails to enhance the protective efficacy of a subunit vaccine against Mycobacterium tuberculosis. Vaccine. 2004;22(5-6):655-659.
  49. Lin SY, Hsieh MJ, Huang SF. Primary Pulmonary Lymphoma-A Case Report. Thoracic Medicine. 2003;18(5):427-432.
  50. Hu HC, Lin CS, Tsao TC, Tsai YH, Hsieh MJ. Antituberculosis drug overdose-induced multiple organ failure - A case report and literature review. Thoracic Medicine. 2003;18(1):64-68.
  51. Tsao TC, Chen CH, Hong JH, Hsieh MJ, Tsao KC, Lee CH. Shifts of T4/T8 T lymphocytes from BAL fluid and peripheral blod by clinical grade in patients with pulmonary tuberculosis. Chest. 2002;122(4):1285-1291.
  52. Chen NH, Liu YC, Tsao TC, et al. Combined bronchoalveolar lavage and polymerase chain reaction in the diagnosis of pulmonary tuberculosis in smear-negative patients. International Journal of Tuberculosis & Lung Disease. 2002 Apr. 2002;6(4):350-355.
  53. Chen KY, Hsieh MJ, Lin MC, Tsai YH, Tsao TC. Pulmonary lymphangioleimotosis (LAM) with initial presentations mimicking bronchial asthma - A case report. Thoracic Medicine. 2001;16(4):282-288.
  54. Wu TC, Lai YF, Chao TY, et al. Pulmonary lymphangioleiomyomatosis in a 29-year-old woman with bilateral spontaneous pneumothorax: case report. Chang Gung Medical Journal. Mar 2000;23(3):164-168.
  55. Tsao TC, Hong JH, Li LF, Hsieh MJ, Liao SK, Chang KS. Imbalances between tumor necrosis factor-alpha and its soluble receptor forms, and interleukin-1beta and interleukin-1 receptor antagonist in BAL fluid of cavitary pulmonary tuberculosis. Chest. 2000;117(1):103-109.
  56. Tsao TC, Li L, Hsieh M, Liao S, Chang KS. Soluble TNF-alpha receptor and IL-1 receptor antagonist elevation in BAL in active pulmonary TB. European Respiratory Journal. 1999;14(3):490-495.
  57. Tsai YH, Lin MC, Hsieh MJ, et al. Spontaneous variability of arterial oxygenation in critically ill mechanically ventilated patients. Intensive Care Medicine. 1999;25(1):37-43.
  58. Li LF, Lin MC, Yang CT, et al. Comparison of indoor allergens, allergic scores, and demographic data in Taiwanese adults with asthma or allergic rhinitis, or both. Journal of the Formosan Medical Association. 1999 Jul. 1999;98(7):486-491.
  59. Li LF, Lin MC, Chen NH, Hsieh MJ, Lee CH, Tsao TC. Serodiagnosis of tuberculosis by enzyme-linked immunosorbent assay for anti-A60 and anti-A38. Chang Gung Med J. 1998;21(3):258-264.
  60. Huang CC, Tsai YH, Lin MC, Yang CT, Hsieh MJ, Lan RS. Respiratory drive and pulmonary mechanics during haemodialysis with ultrafiltration in ventilated patients. Anaesthesia & Intensive Care. 1997;25(5):464-470.
  61. Hsieh MJ, Shieh WB, Chen KS, Yu TJ, Kuo HP, Tsai YH. Pulmonary actinomycosis appearing as a "ball-in-hole" on chest radiography and bronchoscopy. Thorax. 1996;51(2):221-222.
  62. Hsieh MJ, Tsao TC, Cheng PJ. Ovarian hyperstimulation syndrome with minimal ascites and massive pleural effusion: report of a case. J Formos Med Assoc. 1994;93(10):882-884.


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